SHADOW
Recommended use or purpose:
- Minimize cell destruction caused by oxidative stress
- Support healthy immune function
- Reduce skin damage caused by UV radiant
- Facilitate anti-inflammatory actins
Dosage form: Capsule
Medicinal ingredients:
| GliSODin® (Superoxide dismutase/Gliadin complex) | Vit. A |
| Green tea leaf standardized extract | Vit. D |
| Calaguala fern extract |
Original brand: Prestige Nutrition
Product credential: Developed by Quality Alliance International
Overview
SHADOW is an innovative combination product that provides the most powerful natural free radical scavengers. Extensive evidence supporting the efficacy of these ingredients scientifically proves that SHADOW is an advanced combination for safe and effective outdoor protection. It supports healthy immune function, minimizes cell destruction caused by oxidative stress, augments anti-inflammatory function and reduces skin damage caused by UV radiant.
Safety and efficacy of the SHADOW ingredients is very well established based on toxicological and human safety studies.
SHADOW: Minimizes cell destruction caused by oxidative stress, Supports healthy immune function, Reduces skin damage caused by UV radiant, Facilitates anti-inflammatory actins.
GliSODin®
GliSODin® (Superoxide dismutase/Gliadin complex) -a novel natural antioxidant- is one of the three functional ingredients in SHADOW. GliSODin® is the result of 17 years of product development in Europe. 
It is made from the combination of a SOD extracted from melon (Cucumis melo) as the active ingredient and wheat (Triticum vulgare) gliadin as the carrier which protects the enzyme from breakdown by stomach acid.
This novel product promotes powerful antioxidative effect and protects against oxidative stress-induced cell death. Glisodin® was evaluated by many well designed human clinical trials as being an effective antioxidant and immune system modulator. Orally effective SOD-wheat gliadin complex is able to protect against DNA damage according to a double-blind randomised placebo-controlled study.GliSODin® is the first line of natural defense system against free radicals.
Recent studies indicate significant protection against UV-radiation induced oxidative stress and quicker healing compared to a placebo after oral administration of Glisodin®.
Orally active SOD derivative also prevents tumor progression promoted by inflammation which is thought to be through an inflammatory cell-derived super oxide anion scavenging system.
Green tea polyphenols
SHADOW™ also contains high concentration of green tea polyphenols that possess biologic activity in antioxidant, antiangiogenesis, and antiproliferative assays.
There have been more than 150 studies regarding the beneficial effects of green tea on the skin. It was found that green tea polyphenols, especially epigallocatechin-3-gallate (EGCG), inhibited two-stage chemical carcinogenesis and photo carcinogenesis induced by UVB.
Studies show that oral consumption of green tea polyphenols inhibits UV-induced skin tumorigenesis and possesses anti-inflammatory activity. It also decreases oxidative DNA damage, lipid peroxidation and free radical generation.
Green tea components also have potent anti-microbial effects.
Calaguala fern extract
The percolated extract of a tropical fern is another component of SHADOW™ formula. Calaguala fern extract has a proven application in many autoimmune disorders. Recent studies to determine its chemical composition have shown many phenolic compounds that may contribute to the health benefits of this powerful UV protectant.
In addition, preclinical and clinical research has shown that Calaguala extract modulates the immune/inflammatory response and prevents UV-induced skin cancer in several animal models, perhaps by reducing DNA damage. Calaguala has been used in the management of inflammatory skin diseases for more than 30 years without significant side effects.
Calaguala rhizome extract is also used in alternative medicine for the treatment of Vitiligo and Psoriasis.
